Search results for "bladder tumors"

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Multiplicity and history have a detrimental effect on survival in patients with T1G3 bladder tumors selected for conservative treatment.

2008

Purpose: In the absence of Tis tumor we assessed whether history and multiplicity have a detrimental effect on conservative treatment in carefully selected patients with T1G3 bladder carcinoma. Materials and Methods: Between January 1976 and December 1999, 165 select patients with T1G3 bladder tumors were conservatively treated with transurethral resection plus adjuvant intravesical therapy. Patients with concomitant or previous Tis, previous T1G3, tumor size greater than 3 cm and more than 3 lesions were excluded from analysis. Repeat transurethral resection was not routinely performed. However, cytology had to be negative for atypia before the start of adjuvant intravesical therapy. Resul…

NephrologyAdultMalemedicine.medical_specialtyUrologymedicine.medical_treatmentDisease-Free SurvivalPredictive Value of TestsRisk FactorsCytologyInternal medicineCarcinomaAtypiaMedicineHumansSurvival rateAgedNeoplasm StagingAged 80 and overChemotherapyChi-Square Distributionbusiness.industryPatient Selectionbladder tumors T1G3 survival multiplicity historyMiddle Agedmedicine.diseaseSurgerySurvival RateLogistic ModelsUrinary Bladder NeoplasmsChemotherapy AdjuvantConcomitantPredictive value of testsDisease ProgressionUrologic Surgical ProceduresFemaleNeoplasm Recurrence Localbusiness
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Sarcomatoid carcinoma of urinary bladder: Immunohistochemical study of an uncommon case

2002

A case of sarcomatoid carcinoma of the bladder is reported herein. Immunohistochemical staining with human pancytokeratin antibody was negative, while vimentin staining was strongly positive, suggesting a diagnosis of sarcoma of the bladder. Further immunohistochemical analysis revealed positivity for AE1/AE3 cytokeratins, permitting a correct diagnosis of sarcomatoid carcinoma of the bladder. It can be difficult to distinguish between sarcomatoid carcinoma, undifferentiated carcinoma and sarcoma, particularly if the biopsy specimens are of small size. In rare cases, sarcomatoid tumors may express epithelial markers different from those revealed by human pancytokeratin staining. Copyright ©…

Pathologymedicine.medical_specialtyUrinary bladder tumorAE1/AE3 cytokeratinmedicine.medical_treatmentUrologyVimentinSarcomatoid carcinomaCystectomyCytokeratinBiopsyHumansMedicineSarcomatoid carcinomaAgedUrinary bladderbiologymedicine.diagnostic_testAE1/AE3 cytokeratins; Human pancytokeratin; Sarcomatoid carcinoma; Urinary bladder tumors; Urologybusiness.industryCarcinomaSarcomamedicine.diseaseImmunohistochemistrymedicine.anatomical_structureUrinary Bladder NeoplasmsHuman pancytokeratinbiology.proteinKeratinsFemaleSarcomabusinessSpindle cell carcinoma
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